Very-Low-Density Lipoprotein: Complex Particles in Cardiac Energy Metabolism
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Very-Low-Density Lipoprotein: Complex Particles in Cardiac Energy Metabolism
The heart is a major consumer of energy and is able to utilise a wide range of substrates including lipids. Nonesterified fatty acids (NEFA) were thought to be a favoured carbon source, but their quantitative contribution is limited because of their relative histotoxicity. Circulating triacylglycerols (TAGs) in the form of chylomicrons (CMs) and very-low-density lipoprotein (VLDL) are an altern...
متن کاملVery-low density lipoprotein metabolism.
This manuscript was presented in part at the 31st Annual Meeting of the Council on Arteriosclerosis, American Society for the Study of Arteriosclerosis, American Heart Association. 1977. Circulation. 56(Suppl. III): 22. (Abstr.) Received for publication 2 December 1977 and in revised form 9 February 1978. and apoC) contained by negative staining, many disklike structures. The study demonstrated...
متن کاملVery Low Density Lipoprotein Metabolism in Apolipoprotein C1 Transgenic Mice
To study the role of apoC1 in lipoprotein metabolism, we have generated transgenic mice expressing the human APOC1 gene. On a sucrose-rich diet, male transgenic mice with high APOC1 expression in the liver showed elevated levels of serum cholesterol and triglyceride compared with control mice (5.7 6 0.7 and 3.3 6 2.1 vs. 2.7 6 0.1 and 0.4 6 0.1 mmol/liter, respectively). These elevated levels w...
متن کاملInsulin, diabetes and hepatic very-low-density lipoprotein metabolism.
29. Cannon, B. & Nedergaard, J . (1985) Essays Biochem. 20, 110-164 30. Seydoux, J., Chivet, A., Schneider-Picard, G., Bas, S., Mesch, E., Assirnacopoulos-Jeannet, F., Giacobino, J. P. & Girardier, L. ( 1983) Endocrinology (Baltimore) 1 13,604-6 10 31. Rothwell, N. J . & Stock, M. J. (1981) Metab. Clin. Exp. 30, 673-678 Received 3 August 1988 32. Rothwell, N. J., Saville, M. E. & Stock, M. J. (...
متن کاملVery Low Density Lipoprotein (VLDL)
Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...
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ژورنال
عنوان ژورنال: Journal of Lipids
سال: 2011
ISSN: 2090-3030,2090-3049
DOI: 10.1155/2011/189876